his medication is used to treat heart failure. It is used by adults to help prevent the heart failure from getting worse and needing treatment in a hospital. It is also used by children who have heart failure due to an enlarged heart (dilated cardiomyopathy). Heart failure is a condition where your heart does not pump blood as well as it should. Ivabradine works by making your heart beat more slowly. Take this medication by mouth with food as directed by your doctor, usually twice daily. The dosage is based on your medical condition and response to treatment. In children, the dosage is also based on the weight. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Other medications are usually used along with ivabradine to treat heart failure. Carefully follow your doctor’s directions for taking all your medications.
Dizziness or tiredness may occur. If either of these effects persists or worsens, tell your doctor or pharmacist promptly. Ivabradine may rarely cause vision changes such as brief increased brightness, or seeing halos or colored bright lights. Sudden changes in light brightness may set off this effect. If vision changes happen, they usually start within the first 2 months and may go away during treatment or after stopping this medication.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure, liver problems, other heart problems (such as sick sinus syndrome, heart block, slow/irregular heartbeat, pacemaker use).
Other medications can affect the removal of ivabradine from your body, which may affect how ivabradine works. Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, telithromycin), diltiazem, HIV protease inhibitors (such as nelfinavir, ritonavir), nefazodone, rifamycins (such as rifabutin, rifampin), St. John’s wort, verapamil, drugs used to treat seizures (such as carbamazepine, phenobarbital, phenytoin), among others.
This medication is not recommended for use during pregnancy. It may harm an unborn baby. It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breastfeeding while using this drug is not recommended. Consult your doctor before breast-feeding.
Manufacture by Nabiqasim Industries (Pvt) Ltd.
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